Outcomes of patients treated with perioperative epirubicin, cisplatin and fluoropyrimidine chemotherapy for gastro-oesophageal cancer in a New Zealand Cancer Centre
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چکیده
Background In patients with resectable gastric or lower oesophageal adenocarcinomas the perioperative regimen of ECF (epirubicin, cisplatin, fluorouracil) has been proven to down-stage and significantly improve progression-free survival (PFS) and overall survival (OS) compared with surgery alone. This treatment has been applied in our centre since 2007. This is a retrospective audit to review and compare local clinical outcomes and quality to gold standard, taken as the phase III “MAGIC” (Medical Research Council Adjuvant Gastric Infusional Chemotherapy) trial results.
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تاریخ انتشار 2015